eng
Negah Institute for Scientific Communication
( In Cooperation with Negah Scientific Publisher)
International Journal of Biomedicine and Public Health
2588-5375
2019-03-01
2
1
1
7
10.22631/ijbmph.2019.126000.1048
85645
مقاله پژوهشی
Evaluation of the clinical competency level among nurses working in Kermanshah University of Medical Sciences affiliated hospitals
Azam Faraji
faraji.azam@gmail.com
1
Saba Karimi
kariminursing@yahoo.com
2
Akram Ghobadi
ghobadi_a57@yahoo.com
3
Alireza Abdi
a_abdi61@yahoo.com
4
Nursing Department, School of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Nursing Department, School of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Nursing Department, School of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Nursing Department, School of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Introduction:Nurses form build up the greatest portion of health care providers and play a central role in maintaining medical care. Determining the clinical competence level of nurses is an important issue in maintaining standards of care, identifying the educational needs and professional development of nurses. Therefore, the aim of this study was to determine the clinical competency level of nurses who work in Kermanshah University of Medical Sciences affiliated hospitals, in 2014. Methods: This cross sectional study was conducted on 204 nurses working in five educational hospitals affiliated to Kermanshah University of Medical Sciences. Samples were selected based on cluster randomization. The study instruments included demographic information questionnaire and Benner Clinical Competence Questionnaire (CCQ). Data analysis was performed using the SPSS v 16 software. Results: The mean and standard deviation for age and work experience of the subjects were 33.55 ± 6.17 and 9.31 ± 5.74 years, respectively. The mean and standard deviation of the total clinical competency score was 69.56 ± 10.74. The mean score for helping the patient component was 68.11 ± 14.06, training and guidance component was 69.81 ± 11.63, diagnostic measures component was 70.65 ± 15.5, management skills component was 71.04 ± 12.63, therapeutic measures component was 70.56 ± 12.47, quality assurance was 68.32 ± 14.59, and occupational and organizational tasks component was 70.85 ± 11.81. Conclusion: The clinical competence of most samples was categorized as good. According to the results of this study, researchers suggest that clinical competency assessment of nurses should be programmed and performed annually.
https://www.ijbmph.com/article_85645_cd7a1c9f9c96f01a182dc3f745157f44.pdf
Nurses
Clinical Competency
Hospitals
eng
Negah Institute for Scientific Communication
( In Cooperation with Negah Scientific Publisher)
International Journal of Biomedicine and Public Health
2588-5375
2019-03-01
2
1
8
13
10.22631/ijbmph.2018.153711.1081
80780
مقاله پژوهشی
Increased gene expression of integrin β7 in newly diagnosed rheumatoid arthritis patients
Adel Fekri
immono2010@gmail.com
1
Parisa Zafari
pzafari.70@gmail.com
2
Nasrin Iranshahi
nasriniranshahi@yahoo.com
3
Bijan Soleymani
bijansolimani@gmail.com
4
Mahdi Taghaddosi
mtaghad@gmail.com
5
Student Research Committee, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran
Department of Immunology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Student Research Committee, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran
Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
Department of Immunology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
Introduction: Integrin and chemokine receptors play an important role in leukocytes migration and recirculation during autoimmune disorders including rheumatoid arthritis (RA). Normally, gut-homing T cells express CCR9 and integrin α4β7 in order to home back from peripheral blood to the intestinal lamina propria. Our study was conducted to evaluate the chemokine receptor CCR9 and the integrin α4β7 gene expression in circulating leukocytes and lymphocytes among newly diagnosed RA patients and to compare these values with healthy individuals. Methods: In this case-control study, 20 newly diagnosed patients with RA and 20 healthy controls were examined. Peripheral blood samples were acquired from patients and healthy individuals. The total RNA was extracted, then cDNA synthesis was performed. The expression of CCR9 and β7 genes were evaluated by quantitative real-time PCR. The t-test was used to compare gene expression between the groups. Results: We found that RA patients had a significantly higher level of β7 gene expression compared to controls (P=0.007), while there was no significant difference in CCR9 gene expression between 2 groups (P=0.06). Conclusion: Our data showed that the expression of β7 gene increases in RA patients and, similar to IBD, β7 gene can be a candidate target for therapy in RA patients.
https://www.ijbmph.com/article_80780_7fdb8c58d24f99c336acfcaaed54bce3.pdf
Rheumatoid arthritis
Chemokines
Integrins
Gene expression
eng
Negah Institute for Scientific Communication
( In Cooperation with Negah Scientific Publisher)
International Journal of Biomedicine and Public Health
2588-5375
2019-03-01
2
1
14
19
10.22631/ijbmph.2018.126819.1052
67214
مقاله پژوهشی
Epidemiological evaluation of brucellosis in Isfahan Province-Iran in 2016
Elham Karimi-Nazari
1
Motahreh Sadat Hosseini
hosseinimsh@yahoo.com
2
Hossein Jadidi
3
Vida Rahimi
4
Ali Heidari
5
Nutrition and Food Safety Research Center, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran
Department of Food Hygiene and Safety, Faculty of Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Research Committee and Department of Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran
Department of Food Hygiene and Safety, Faculty of Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Zoonotic Diseases Research Center, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Introduction: Brucellosis is one of the most common zoonosis diseases that can be seen in many developing countries, including Iran. The aim of this study was to determine the prevalence of brucellosis in Isfahan province. Methods: This is a cross-sectional study in which all newly reported cases of brucellosis in Isfahan city in 2016 were studied. Sampling was done through numerical method. The statistical tests used in this study were one-way ANOVA and two-sample T-test. Results: The incidence rate of brucellosis in Isfahan province in 2016 was 19.78 per 100,000. Majority of cases (590, 67.8%) were men with a mean age of 31.62 ± 20.04 years old and 32.2% (280 cases) were women with a mean age of 33.35 ± 20.26 years old. Friedan had the highest incidence rate of brucellosis (204.47 per 100,000) while Isfahan had the lowest incidence rate (1.81 per 100,000). There was a significant relationship between occupational variables (P = 0.001), history of contact with the livestock (P = 0.0001), non-pasteurized dairy consumption (P = 0.0001), and the incidence of the disease (P = 0.003) in urban and rural areas. Conclusion: The incidence rate of brucellosis in Isfahan is classified as a very low. The disease is more common in rural areas than in urban areas. Therefore, educational, preventive and therapeutic measures in rural areas, particularly in those involved with animal husbandry and homemaking, have priority over urban areas.
https://www.ijbmph.com/article_67214_b56b8f212db4d63ca1203c853e173b98.pdf
Brucellosis
Epidemiology
Iran
eng
Negah Institute for Scientific Communication
( In Cooperation with Negah Scientific Publisher)
International Journal of Biomedicine and Public Health
2588-5375
2019-03-31
2
1
20
26
10.22631/ijbmph.2018.125835.1047
85666
مقاله پژوهشی
Application of job safety analysis and inspecting the changes in identification of hazards in a cement industry in Fars province in 2017
Zeinab Nezamodini
z_nezamodin@yahoo.com
1
Sedigheh Ahmadabadi
nazi.mosavianasl@gmail.com
2
Zeinab Mosavianasl
z.mosavianasl@gmail.com
3
Department of Occupational Health Engineering, School of Public Health, Ahvaz JundiShapur University of Medical Sciences, Ahvaz, Iran
Department of Occupational Health Engineering, School of Public Health, Ahvaz JundiShapur University of Medical Sciences, Ahvaz, Iran
Department of Occupational Health and Safety Engineering, School of Health, Larestan University of Medical Sciences, Larestan, Iran
Introduction: Every year, many workers lose their lives or suffer serious injuries due to various workplace accidents, and it is essential to investigate and identify hazards to prevent accidents. Therefore, the purpose of the current study was to investigate occupational hazards using job safety analysis and inspecting the changes in identification of hazards in a cement industry. Methods: This cross-sectional study was conducted in 2017. Fifteen critical job positions that bear potential health threats were identified in a cement factory in Fars province. The hazards of each position were investigated using job safety analysis and inspecting the changes. Results: The highest scored cause of accidents among the evaluated hazards was human error with the score of 37.1%. Economic outcomes (56.1%) was rated higher compared to human and environmental outcomes and human causes (58.9%) was rated higher compared to management, design, and structural reasons. Furthermore, management changes (55.3%) prioritized design and structural changes. Conclusion: The change analysis is a powerful way to reveal the contemporary defects in an organization or system, and can be used to identify deficiencies and hazards, ways to fix the defects and the scope of the problem. Executing the specified changes, remarkably improves the safety of the organization and controls the existing hazards.
https://www.ijbmph.com/article_85666_821725e17656fb711e8b7d978f24aaa8.pdf
Change analysis
Job safety analysis
cement industry
eng
Negah Institute for Scientific Communication
( In Cooperation with Negah Scientific Publisher)
International Journal of Biomedicine and Public Health
2588-5375
2019-03-01
2
1
27
31
10.22631/ijbmph.2018.143108.1070
80774
مقاله پژوهشی
Anticoagulant and cytotoxic assessment of L-amino acid oxidase from Indian cobra (Naja naja) venom
Neema K N
neema.mtech@yahoo.in
1
Venugopal B
venu.1726@gmail.com
2
Vivek H K
vivek_hk@hotmail.com
3
B S Priya
priyabs@gmail.com
4
Nanjunda Swamy S
nanju_chem@yahoo.com
5
Department of Biotechnology, JSS Science & Technology university
Department of Biochemistry, JSS University, Mysore
Department of Biotechnology, JSS Science & technology university
Deaprtment of Chemistry, University of Mysore
Department of Biotechnology, JSS Science & Technology
Introduction: Snake venom L-amino acid oxidase (SV-LAAO) has promising therapeutic prospects because of its effects on various biological functions. Purified Naja naja venom enzyme L-amino acid oxidase (NnLAAO) was studied to examine its anticoagulant and cytotoxic properties. Methods: Activated partial prothrombin time (APPT) assay and prothrombin time (PT) both of these assays are used to access the anti-coagulant property of NnLAAO on human blood sample. Sulforhodamine B (SRB) protocol is performed on MDA MB-231and HCT 116 cell, which are treated with different doses (0.4µg-100µg) of NnLAAO for 48h incubation time, respectively, and the percentage of inhibition was compared with oxaloplatin as positive control. Results: NnLAAO significantly prolonged the APPT and showed a negligible effect on the PT. NnLAAO inhibited cytotoxicity in a dose-dependent manner in both breast cancer MDA MB-231 and colon adenocarcinoma (HCT-116) cell lines with 60% and 78% of inhibition respectively. Conclusion: The NnLAAO enzyme of Indian cobra venom is a promising anticoagulant as well an anticancer agent for various cell lines because of its efficiency and specificity, as it will offer better treatment and response with fewer side effects.
https://www.ijbmph.com/article_80774_84aa47629fb5542618cc9665539446bc.pdf
L-amino acid oxidase
anticoagulants
Cytotoxic
HCT-116
eng
Negah Institute for Scientific Communication
( In Cooperation with Negah Scientific Publisher)
International Journal of Biomedicine and Public Health
2588-5375
2019-03-30
2
1
32
36
10.22631/ijbmph.2019.127070.1053
85665
مقاله پژوهشی
Antibiotic resistance pattern and assessment of Temorina gene in clinical strains of extended-spectrum beta-lactamase enzyme producing Escherichia coli isolated from patients, Babol City, Mazandaran Province
Zohreh Eslam Doost
sama_tanha0123@yahoo.com
1
Esmaeil Fattahi
microbiol_sci2013@yahoo.com
2
Samaneh Rouhi
roohi.samaneh@yahoo.com
3
Karo Servatyari
servatyarikaro@yahoo.com
4
Pegah Shakib
shakib.pegah@yahoo.com
5
Saba Asadollahi
hamidmoqhtader@yahoo.com
6
Fatemeh Zaboli
microbiol_sci@yahoo.com
7
Department of Biology, Faculty of Agriculture and Food Industry, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
Department of Biology, Faculty of Agriculture and Food Industry, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran
Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran
Razi Herbal Medicines Center, Lorestan University of Medical Sciences, Khorramabad, Iran
Student Research Committee, Department of Microbiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
Department of Biology, Faculty of Agriculture and Food Industry, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
Introduction: Escherichia coli (E. coli) bacteria are a common cause of various clinical infections. Resistance of this bacteria to several common antibiotics due to production of extended spectrum beta-lactamase (ESBL) enzyme has caused therapeutic problems. The aim of this study was to determine the resistance pattern to beta-lactam antibiotics and also to assess the Temorina (TEM) gen in the E. coli strains isolated from the patients in Babol, Iran. Methods: This cross-sectional study was conducted in 2014 at Babol County, Iran. The E. coli strains were isolated and identified by standard laboratory tests. The sensitivity test to beta-lactam antibiotics was performed by combined disk method. The TEM gene was identified in the resistant strains by the polymerase chain reaction (PCR) method. The data were analyzed by SPSS 20 and by using t-test and Chi2 tests. Results: Of the 10341 clinical samples, 525 E. coli isolated of which 200 (38%) were ESBL-producing strains. Piperacillin-tazobactam, amikacin, ampicillin-sulbactam and ampicillin (98%, 90.33%, 86.4% and 76.60%, respectively) had the most inhibition effect on the strains. Highest antibiotic resistance was observed for ceftriaxone (43.80%) and ciprofloxacin (38.74%). PCR showed that 80% (N=160) of the resistant strains had the TEM gene. There was a statistically significant correlation between TEM gene and the production of ESBL (P<0.05). Conclusion: Resistance to antibiotics was observed in this study. Resistant and ESBL-producing strains of E. coli had TEM gene. The clinicians should be aware of antibiotic resistant pattern to choose effective medicines for treatment of these infections.
https://www.ijbmph.com/article_85665_d96d18dec70fff9f3a69b7adec4d014b.pdf
E. coli
Antibiotic resistance pattern
Extended-spectrum beta-lactamase
Temorina